Publications

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2019
P. Chotsiri, Zongo, I. , Milligan, P. , Compaore, Y. D. , Some, A. F. , Chandramohan, D. , Hanpithakpong, W. , Nosten, F. , Greenwood, B. , Rosenthal, P. J. , White, N. J. , Ouedraogo, J. B. , and Tarning, J. , “Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children”, Nat Commun, vol. 10, no. 1, p. 480, 2019.
C. E. G. Mercado, Lawpoolsri, S. , Sudathip, P. , Kaewkungwal, J. , Khamsiriwatchara, A. , Pan-Ngum, W. , Yimsamran, S. , Lawawirojwong, S. , Ho, K. , Ekapirat, N. , Maude, R. R. , Wiladphaingern, J. , Carrara, V. I. , Day, N. P. J. , Dondorp, A. M. , and Maude, R. J. , “Spatiotemporal epidemiology, environmental correlates, and demography of malaria in Tak Province, Thailand (2012-2015)”, Malar J, vol. 18, no. 1, p. 240, 2019.
2017
P. Ya-Umphan, Cerqueira, D. , Parker, D. M. , Cottrell, G. , Poinsignon, A. , Remoue, F. , Brengues, C. , Chareonviriyaphap, T. , Nosten, F. , and Corbel, V. , “Use of an Anopheles Salivary Biomarker to Assess Malaria Transmission Risk Along the Thailand-Myanmar Border”, J Infect Dis, vol. 215, no. 3, pp. 396-404, 2017.
2016
R. Cross, Ling, C. , Day, N. P. , McGready, R. , and Paris, D. H. , “Revisiting doxycycline in pregnancy and early childhood--time to rebuild its reputation?”, Expert Opin Drug Saf, vol. 15, no. 3, pp. 367-82, 2016.
2014
M. Venkatesan, Gadalla, N. B. , Stepniewska, K. , Dahal, P. , Nsanzabana, C. , Moriera, C. , Price, R. N. , Martensson, A. , Rosenthal, P. J. , Dorsey, G. , Sutherland, C. J. , Guerin, P. , Davis, T. M. , Menard, D. , Adam, I. , Ademowo, G. , Arze, C. , Baliraine, F. N. , Berens-Riha, N. , Bjorkman, A. , Borrmann, S. , Checchi, F. , Desai, M. , Dhorda, M. , Djimde, A. A. , El-Sayed, B. B. , Eshetu, T. , Eyase, F. , Falade, C. , Faucher, J. F. , Froberg, G. , Grivoyannis, A. , Hamour, S. , Houze, S. , Johnson, J. , Kamugisha, E. , Kariuki, S. , Kiechel, J. R. , Kironde, F. , Kofoed, P. E. , LeBras, J. , Malmberg, M. , Mwai, L. , Ngasala, B. , Nosten, F. , Nsobya, S. L. , Nzila, A. , Oguike, M. , Otienoburu, S. D. , Ogutu, B. , Ouedraogo, J. B. , Piola, P. , Rombo, L. , Schramm, B. , Some, A. F. , Thwing, J. , Ursing, J. , Wong, R. P. , Zeynudin, A. , Zongo, I. , Plowe, C. V. , Sibley, C. H. , Group, A. Molecular, and Wwarn, A. L. , “Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine”, Am J Trop Med Hyg, vol. 91, no. 4, pp. 833-43, 2014.
2012
R. Rueangweerayut, Phyo, A. P. , Uthaisin, C. , Poravuth, Y. , Binh, T. Q. , Tinto, H. , Penali, L. K. , Valecha, N. , Tien, N. T. , Abdulla, S. , Borghini-Fuhrer, I. , Duparc, S. , Shin, C. S. , and Fleckenstein, L. , “Pyronaridine-artesunate versus mefloquine plus artesunate for malaria”, N Engl J Med, vol. 366, no. 14, pp. 1298-309, 2012.
2011
S. Canavati, Plugge, E. , Suwanjatuporn, S. , Sombatrungjaroen, S. , and Nosten, F. , “Barriers to immunization among children of migrant workers from Myanmar living in Tak province, Thailand”, Bull World Health Organ, vol. 89, no. 7, pp. 528-31, 2011.
2009
J. Zwang, Olliaro, P. , Barennes, H. , Bonnet, M. , Brasseur, P. , Bukirwa, H. , Cohuet, S. , d'Alessandro, U. , Djimde, A. , Karema, C. , Guthmann, J. P. , Hamour, S. , Ndiaye, J. L. , Martensson, A. , Rwagacondo, C. , Sagara, I. , Same-Ekobo, A. , Sirima, S. B. , van den Broek, I. , Yeka, A. , Taylor, W. R. , Dorsey, G. , and Randrianarivelojosia, M. , “Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis”, Malar J, vol. 8, p. 203, 2009.
M. T. Ambler, Dubowitz, L. M. , Arunjerdja, R. , Hla, E. P. , Thwai, K. L. , Viladpainguen, J. , Singhasivanon, P. , Luxemburger, C. , Nosten, F. , and McGready, R. , “The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria”, Malar J, vol. 8, p. 207, 2009.
2008
J. P. Guthmann, Pittet, A. , Lesage, A. , Imwong, M. , Lindegardh, N. , M. Lwin, M. , Zaw, T. , Annerberg, A. , de Radigues, X. , and Nosten, F. , “Plasmodium vivax resistance to chloroquine in Dawei, southern Myanmar”, Trop Med Int Health, vol. 13, no. 1, pp. 91-8, 2008.
2007
B. Janssens, van Herp, M. , Goubert, L. , Chan, S. , Uong, S. , Nong, S. , Socheat, D. , Brockman, A. , Ashley, E. A. , and Van Damme, W. , “A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia”, Trop Med Int Health, vol. 12, no. 2, pp. 251-9, 2007.
2006
F. Smithuis, Kyaw, M. K. , Phe, O. , Aye, K. Z. , Htet, L. , Barends, M. , Lindegardh, N. , Singtoroj, T. , Ashley, E. , Lwin, S. , Stepniewska, K. , and White, N. J. , “Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison”, Lancet, vol. 367, no. 9528, pp. 2075-85, 2006.
E. A. Ashley, Stepniewska, K. , Lindegardh, N. , McGready, R. , Hutagalung, R. , Hae, R. , Singhasivanon, P. , White, N. J. , and Nosten, F. , “Population pharmacokinetic assessment of a new regimen of mefloquine used in combination treatment of uncomplicated falciparum malaria”, Antimicrob Agents Chemother, vol. 50, no. 7, pp. 2281-5, 2006.
2005
A. Dondorp, Nosten, F. , Stepniewska, K. , Day, N. , and White, N. , “Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial”, Lancet, vol. 366, no. 9487, pp. 717-25, 2005.
2004
M. Adjuik, Babiker, A. , Garner, P. , Olliaro, P. , Taylor, W. , and White, N. , “Artesunate combinations for treatment of malaria: meta-analysis”, Lancet, vol. 363, no. 9402. pp. 9-17, 2004.
F. Smithuis, van der Broek, I. , Katterman, N. , Kyaw, M. K. , Brockman, A. , Lwin, S. , and White, N. J. , “Optimising operational use of artesunate-mefloquine: a randomised comparison of four treatment regimens”, Trans R Soc Trop Med Hyg, vol. 98, no. 3, pp. 182-92, 2004.
2002
J. P. Guthmann, Kasparian, S. , Phetsouvanh, R. , Nathan, N. , Garcia, M. , Phompida, S. , Brockman, A. , Gastellu, M. , and Legros, D. , “The efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria in Laos”, Ann Trop Med Parasitol, vol. 96, no. 6, pp. 553-7, 2002.
M. van Vugt, Leonardi, E. , Phaipun, L. , Slight, T. , Thway, K. L. , McGready, R. , Brockman, A. , Villegas, L. , Looareesuwan, S. , White, N. J. , and Nosten, F. , “Treatment of uncomplicated multidrug-resistant falciparum malaria with artesunate-atovaquone-proguanil”, Clinical Infectious Diseases, vol. 35, no. 12, pp. 1498-504., 2002.
2001
R. N. Price, Simpson, J. A. , Nosten, F. , Luxemburger, C. , Hkirjaroen, L. , F. Kuile, T. , Chongsuphajaisiddhi, T. , and White, N. J. , “Factors contributing to anemia after uncomplicated falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 65, no. 5, pp. 614-22., 2001.
2000
M. van Vugt, Looareesuwan, S. , Wilairatana, P. , McGready, R. , Villegas, L. , Gathmann, I. , Mull, R. , Brockman, A. , White, N. J. , and Nosten, F. , “Artemether-lumefantrine for the treatment of multidrug-resistant falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 94, no. 5, pp. 545-8., 2000.
M. van Vugt, Angus, B. J. , Price, R. N. , Mann, C. , Simpson, J. A. , Poletto, C. , Htoo, S. E. , Looareesuwan, S. , White, N. J. , and Nosten, F. , “A case-control auditory evaluation of patients treated with artemisinin derivatives for multidrug-resistant Plasmodium falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 62, no. 1, pp. 65-9, 2000.
A. Brockman, Price, R. N. , van Vugt, M. , Heppner, D. G. , Walsh, D. , Sookto, P. , Wimonwattrawatee, T. , Looareesuwan, S. , White, N. J. , and Nosten, F. , “Plasmodium falciparum antimalarial drug susceptibility on the north- western border of Thailand during five years of extensive use of artesunate-mefloquine”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 94, no. 5, pp. 537-44., 2000.
1999
M. van Vugt, Wilairatana, P. , Gemperli, B. , Gathmann, I. , Phaipun, L. , Brockman, A. , Luxemburger, C. , White, N. J. , Nosten, F. , and Looareesuwan, S. , “Efficacy of six doses of artemether-lumefantrine (benflumetol) in multidrug-resistant Plasmodium falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 60, no. 6, pp. 936-42, 1999.
R. E. Paul, Brockman, A. , Price, R. N. , Luxemburger, C. , White, N. J. , Looareesuwan, S. , Nosten, F. , and Day, K. P. , “Genetic analysis of Plasmodium falciparum infections on the north- western border of Thailand”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 93, no. 6, pp. 587-93, 1999.
M. van Vugt, Ezzet, F. , Nosten, F. , Gathmann, I. , Wilairatana, P. , Looareesuwan, S. , and White, N. J. , “No evidence of cardiotoxicity during antimalarial treatment with artemether-lumefantrine”, American Journal of Tropical Medicine and Hygiene, vol. 61, no. 6, pp. 964-7, 1999.
R. Price, Simpson, J. A. , Teja-Isavatharm, P. , Than, M. M. , Luxemburger, C. , Heppner, D. G. , Chongsuphajaisiddhi, T. , Nosten, F. , and White, N. J. , “Pharmacokinetics of mefloquine combined with artesunate in children with acute falciparum malaria”, Antimicrob Agents Chemother, vol. 43, no. 2, pp. 341-6, 1999.
R. Price, Nosten, F. , Simpson, J. A. , Luxemburger, C. , Phaipun, L. , F. Kuile, T. , van Vugt, M. , Chongsuphajaisiddhi, T. , and White, N. J. , “Risk factors for gametocyte carriage in uncomplicated falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 60, no. 6, pp. 1019-23, 1999.
C. Luxemburger, van Vugt, M. , Jonathan, S. , McGready, R. , Looareesuwan, S. , White, N. J. , and Nosten, F. , “Treatment of vivax malaria on the western border of Thailand”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 93, no. 4, pp. 433-8, 1999.
1998
R. Price, Luxemburger, C. , van Vugt, M. , Nosten, F. , Kham, A. , Simpson, J. , Looareesuwan, S. , Chongsuphajaisiddhi, T. , and White, N. J. , “Artesunate and mefloquine in the treatment of uncomplicated multidrug- resistant hyperparasitaemic falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 92, no. 2, pp. 207-11, 1998.
R. Price, van Vugt, M. , Nosten, F. , Luxemburger, C. , Brockman, A. , Phaipun, L. , Chongsuphajaisiddhi, T. , and White, N. , “Artesunate versus artemether for the treatment of recrudescent multidrug-resistant falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 59, no. 6, pp. 883-8, 1998.
C. Luxemburger, Nosten, F. , Kyle, D. E. , Kiricharoen, L. , Chongsuphajaisiddhi, T. , and White, N. J. , “Clinical features cannot predict a diagnosis of malaria or differentiate the infecting species in children living in an area of low transmission”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 92, no. 1, pp. 45-9, 1998.
C. Luxemburger, van Vugt, M. , Slight, T. , Price, R. N. , Chongsuphajaisiddhi, T. , Chanthavanich, P. , White, N. J. , and Nosten, F. , “Early vomiting of mefloquine in children with malaria is not modified by the timing of antipyretic treatment”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 92, no. 5, pp. 562-3, 1998.
C. Luxemburger, Brockman, A. , Silamut, K. , Nosten, F. , van Vugt, M. , Gimenez, F. , Chongsuphajaisiddhi, T. , and White, N. J. , “Two patients with falciparum malaria and poor in vivo responses to artesunate”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 92, no. 6, pp. 668-9, 1998.
1997
R. N. Price, Nosten, F. , Luxemburger, C. , van Vugt, M. , Phaipun, L. , Chongsuphajaisiddhi, T. , and White, N. J. , “Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 91, no. 5, pp. 574-7, 1997.
C. Luxemburger, Ricci, F. , Nosten, F. , Raimond, D. , Bathet, S. , and White, N. J. , “The epidemiology of severe malaria in an area of low transmission in Thailand”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 91, no. 3, pp. 256-62, 1997.
F. Nosten, Luxemburger, C. , Kyle, D. E. , Gordon, D. M. , Ballou, W. R. , Sadoff, J. C. , Brockman, A. , Permpanich, B. , Chongsuphajaisiddhi, T. , and Heppner, D. G. , “Phase I trial of the SPf66 malaria vaccine in a malaria-experienced population in Southeast Asia”, Am J Trop Med Hyg, vol. 56, no. 5, pp. 526-32, 1997.
1996
R. N. Price, Nosten, F. , Luxemburger, C. , F. Kuile, T. , Paiphun, L. , Chongsuphajaisiddhi, T. , and White, N. J. , “Effects of artemisinin derivatives on malaria transmissibility”, Lancet, vol. 347, pp. 1654-8, 1996.
D. B. Bethell, Phuong, P. T. , Phuong, C. X. , Nosten, F. , Waller, D. , Davis, T. M. , Day, N. P. , Crawley, J. , Brewster, D. , Pukrittayakamee, S. , and White, N. J. , “Electrocardiographic monitoring in severe falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 90, no. 3. pp. 266-9, 1996.
C. Luxemburger, Price, R. N. , Nosten, F. , F. Kuile, T. , Chongsuphajaisiddhi, T. , and White, N. J. , “Mefloquine in infants and young children”, Annals of Tropical Paediatrics, vol. 16, no. 4, pp. 281-6, 1996.
F. Nosten, Luxemburger, C. , Kyle, D. E. , Ballou, W. R. , Wittes, J. , Wah, E. , Chongsuphajaisiddhi, T. , Gordon, D. M. , White, N. J. , Sadoff, J. C. , and Heppner, D. G. , “Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand.”, Lancet, vol. 348, pp. 701-7, 1996.
1995
R. N. Price, Nosten, F. , Luxemburger, C. , Kham, A. , Brockman, A. , Chongsuphajaisiddhi, T. , and White, N. J. , “Artesunate versus artemether in combination with mefloquine for the treatment of multidrug-resistant falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 89, no. 5, pp. 523-7, 1995.
D. Waller, Krishna, S. , Crawley, J. , Miller, K. , Nosten, F. , Chapman, D. , F. Kuile, T. , Craddock, C. , Berry, C. , and Holloway, P. A. , “Clinical features and outcome of severe malaria in Gambian children”, Clinical Infectious Diseases, vol. 21, no. 3, pp. 577-87, 1995.
W. R. Ballou, Blood, J. , Chongsuphajaisiddhi, T. , Gordon, D. M. , Heppner, D. G. , Kyle, D. E. , Luxemburger, C. , Nosten, F. , Sadoff, J. C. , and Singhasivanon, P. , “Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study”, PARASITOLOGY, vol. 110, no. Suppl. pp. S25-36, 1995.
T. F. Kuile, Nosten, F. , Luxemburger, C. , Kyle, D. , Teja-Isavatharm, P. , Phaipun, L. , Price, R. , Chongsuphajaisiddhi, T. , and White, N. J. , “Mefloquine treatment of acute falciparum malaria: a prospective study of non-serious adverse effects in 3673 patients”, Bulletin of the World Health Organization, vol. 73, no. 5, pp. 631-42, 1995.
C. Luxemburger, Nosten, F. , Raimond, S. D. , Chongsuphajaisiddhi, T. , and White, N. J. , “Oral artesunate in the treatment of uncomplicated hyperparasitemic falciparum malaria”, American Journal of Tropical Medicine and Hygiene, vol. 53, no. 5, pp. 522-5, 1995.
T. F. Kuile, Luxemburger, C. , Nosten, F. , Thwai, K. L. , Chongsuphajaisiddhi, T. , and White, N. J. , “Predictors of mefloquine treatment failure: a prospective study of 1590 patients with uncomplicated falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 89, no. 6, pp. 660-4, 1995.
1994
T. F. Kuile, Teja-Isavatharm, P. , Edstein, M. D. , Keeratithakul, D. , Dolan, G. , Nosten, F. , Phaipun, L. , Webster, H. K. , and White, N. J. , “Comparison of capillary whole blood, venous whole blood, and plasma concentrations of mefloquine, halofantrine, and desbutyl-halofantrine measured by high-performance liquid chromatography”, American Journal of Tropical Medicine and Hygiene, vol. 51, no. 6, pp. 778-84, 1994.
S. Krishna, Waller, D. W. , F. Kuile, T. , Kwiatkowski, D. , Crawley, J. , Craddock, C. F. , Nosten, F. , Chapman, D. , Brewster, D. , and Holloway, P. A. , “Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 88, no. 1. pp. 67-73, 1994.
C. Luxemburger, F. Kuile, T. , Nosten, F. , Dolan, G. , Bradol, J. H. , Phaipun, L. , Chongsuphajaisiddhi, T. , and White, N. J. , “Single day mefloquine-artesunate combination in the treatment of multi- drug resistant falciparum malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 88, no. 2, pp. 213-7, 1994.
1993
T. F. Kuile, Dolan, G. , Nosten, F. , Edstein, M. D. , Luxemburger, C. , Phaipun, L. , Chongsuphajaisiddhi, T. , Webster, H. K. , and White, N. J. , “Halofantrine versus mefloquine in treatment of multidrug-resistant falciparum malaria”, Lancet, vol. 341, pp. 1044-9, 1993.
1992
T. F. Kuile, Nosten, F. , Chongsuphajaisiddhi, T. , Holloway, P. , Maelankirri, L. , and White, N. J. , “Absorption of intramuscular phenobarbitone in children with severe falciparum malaria”, European Journal of Clinical Pharmacology, vol. 42, no. 1. pp. 107-10, 1992.
N. J. White, Waller, D. , Crawley, J. , Nosten, F. , Chapman, D. , Brewster, D. , and Greenwood, B. M. , “Comparison of artemether and chloroquine for severe malaria in Gambian children”, Lancet, vol. 339, pp. 317-21, 1992.
T. F. Kuile, Nosten, F. , Thieren, M. , Luxemburger, C. , Edstein, M. D. , Chongsuphajaisiddhi, T. , Phaipun, L. , Webster, H. K. , and White, N. J. , “High-dose mefloquine in the treatment of multidrug-resistant falciparum malaria”, Journal of Infectious Diseases, vol. 166, no. 6, pp. 1393-400, 1992.
1991
D. Waller, Crawley, J. , Nosten, F. , Chapman, D. , Krishna, S. , Craddock, C. , Brewster, D. , and White, N. J. , “Intracranial pressure in childhood cerebral malaria”, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 85, no. 3, pp. 362-4, 1991.
F. Nosten, F. Kuile, T. , Chongsuphajaisiddhi, T. , K. Bangchang, N. , Karbwang, J. , and White, N. J. , “Mefloquine pharmacokinetics and resistance in children with acute falciparum malaria”, British Journal of Clinical Pharmacology, vol. 31, no. 5, pp. 556-9, 1991.
F. Nosten, F. Kuile, T. , Chongsuphajaisiddhi, T. , Luxemburger, C. , Webster, H. K. , Edstein, M. , Phaipun, L. , Thew, K. L. , and White, N. J. , “Mefloquine-resistant falciparum malaria on the Thai-Burmese border”, Lancet, vol. 337, no. 8750, pp. 1140-3, 1991.